![]() But it's important to know that having a mastectomy does not always stop cancer from recurring. If cancer comes back after being treated with a lumpectomy and radiation, doctors will often recommend a mastectomy to reduce the risk of the cancer recurring once again. A local recurrence after lumpectomy and radiation therapy has a more favourable prognosis than cancer that comes back in other organs (called distant recurrence, or distant metastasis). However, hormone receptor–positive tumours sometimes recur years after treatment has finished.įind out more about hormone receptor status testing.Ĭancer that comes back in the same breast is called a local recurrence. As a result, hormone receptor–positive tumours generally have a better prognosis in the short term than hormone receptor–negative tumours. This means that they grow more slowly, are lower grade and have a lower risk of spreading. They are usually less aggressive than hormone receptor–negative tumours (which don't have ERs or PRs). Hormone receptor–positive tumours have ERs, PRs or both. Knowing the hormone receptor status of the tumour helps doctors predict how well hormone therapy will work and what other treatments may be effective. Once they attach, the hormones can affect the behaviour or growth of the cells.īreast cancer cells that have ERs and PRs need these hormones to grow and divide. These receptors are where the hormones attach to the cells. Some types of breast cancer cells have estrogen receptors (ERs) and progesterone receptors (PRs) on their surface or inside them. Only a doctor familiar with your medical history, the type, stage and other features of the cancer, the treatments chosen and the response to treatment can put all of this information together with survival statistics to arrive at a prognosis and the chances of survival.ĭoctors use different prognostic and predictive factors for newly diagnosed and recurrent breast cancers.Įstrogen and progesterone can help some breast cancer cells grow. They both play a part in deciding on a prognosis and a treatment plan just for you. Prognostic and predictive factors are often discussed together. The doctor will also look at predictive factors, which influence how a cancer will respond to a certain treatment and how likely it is that the cancer will come back after treatment. The doctor will look at certain characteristics of the person and aspects of the cancer, such as its stage and grade and the size of the tumour. Prognosis and survival depend on many factors. Survival is the percentage of people with a disease who are alive at some point in time after their diagnosis. ![]() ![]() A prognosis is the doctor’s best estimate of how cancer will affect you and how it will respond to treatment.
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